Effect of Moringa oleifera Stem Extract on the Regulation of Gastrointestinal Motility of Mice

Key words: 
• Moringa oleifera stem extract /
• change in body weight /
• constipation model /
• motility of intestines

Abstract: Healthy Kunming mice were selected and randomly divided into 14 groups,including blank control group,constipation model group,and the other 12 groups that were administered Moringa oleifera stem extracts.The Imodium constipation rat model was established. The body weight of normal mice were measured before and after the mice were administrated the stem extracts,and the migration distance of Indian ink propulsion of the small intestines in mice were measured to observe the motility of the small intestines in mice. The mice were subjected to continuous intragastric infusion for 7 days. The results showed that different portions of M. oleifera stem extracts produced no obvious effect on the growth of the body weight of the mice. The water phase portions from the xylem and phloem exstracts showed a significant effect on the motility of the small intestines in mice,and their small intestine propulsion rates were 48. 89% and 48. 69%,respectively. The results indicated that the M.oleifera stem extracts had an obvious effect on improving of the constipation in mice,and hence show a broad prospect for development.