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Volume 6 Issue 2
Apr.  2015
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Article Navigation >  Journal of Tropical Biology  > 2015  >  6(2): 163-167

CAI Caihong, MEI Wenli, WANG Hui, DONG Wenhua, TAN Guanghong, DAI Haofu. Biological Activity of the Extracts from Ancistrocladus tectorius[J]. Journal of Tropical Biology, 2015, 6(2): 163-167. doi: 10.15886/j.cnki.rdswxb.2015.02.010
Citation: CAI Caihong, MEI Wenli, WANG Hui, DONG Wenhua, TAN Guanghong, DAI Haofu. Biological Activity of the Extracts from Ancistrocladus tectorius[J]. Journal of Tropical Biology, 2015, 6(2): 163-167. doi: 10.15886/j.cnki.rdswxb.2015.02.010
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Biological Activity of the Extracts from Ancistrocladus tectorius

doi: 10.15886/j.cnki.rdswxb.2015.02.010

  • 1. Institute of Tropical Bioscience and Biotechnology/Ministry of Agriculture Key Laboratory of Biology and Genetic Resources of Tropical Crops/Hainan Key Laboratory for Research and Development of Natural Products from Li Folk Medicine, CATAS, Haikou 571101, China;

  • 2. Key Laboratory for Tropical Diseases, Hainan Medical College, Haikou 571101, China

  • Received Date: 2015-01-16
  • Ancistrocladus tectorius was extracted with ethyl alcohol（ Et OH）,and the active constituents of the Et OH and their biological activities against malaria were determined. Mice infected with Plasmodium berghei were treated with the Et OH extract,and its cytotoxic activity was assayed by the MTT method. The antimicrobial activities of the Et OH extract were tested by the paper disk diffusion method,and its acetylcholinesterase inhibitory activity was detected by using the Ellman’s colorimetric method. The results indicated that the Et OH extract of A.tectorius inhibited the growth of malaria parasites and improved the survival rate of the mice infected with P.berghei. It also possessed inhibitory activity against K562,SGC-7721 and BEL-7402 cell lines,as well as human and agricultural pathogens. Moreover,it showed lower inhibitory activity against acetylcholinesterase than Tacrine.
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Biological Activity of the Extracts from Ancistrocladus tectorius

doi: 10.15886/j.cnki.rdswxb.2015.02.010
  • 1. Institute of Tropical Bioscience and Biotechnology/Ministry of Agriculture Key Laboratory of Biology and Genetic Resources of Tropical Crops/Hainan Key Laboratory for Research and Development of Natural Products from Li Folk Medicine, CATAS, Haikou 571101, China;
  • 2. Key Laboratory for Tropical Diseases, Hainan Medical College, Haikou 571101, China
  • Received Date: 2015-01-16

Abstract: Ancistrocladus tectorius was extracted with ethyl alcohol（ Et OH）,and the active constituents of the Et OH and their biological activities against malaria were determined. Mice infected with Plasmodium berghei were treated with the Et OH extract,and its cytotoxic activity was assayed by the MTT method. The antimicrobial activities of the Et OH extract were tested by the paper disk diffusion method,and its acetylcholinesterase inhibitory activity was detected by using the Ellman’s colorimetric method. The results indicated that the Et OH extract of A.tectorius inhibited the growth of malaria parasites and improved the survival rate of the mice infected with P.berghei. It also possessed inhibitory activity against K562,SGC-7721 and BEL-7402 cell lines,as well as human and agricultural pathogens. Moreover,it showed lower inhibitory activity against acetylcholinesterase than Tacrine.

CAI Caihong, MEI Wenli, WANG Hui, DONG Wenhua, TAN Guanghong, DAI Haofu. Biological Activity of the Extracts from Ancistrocladus tectorius[J]. Journal of Tropical Biology, 2015, 6(2): 163-167. doi: 10.15886/j.cnki.rdswxb.2015.02.010
Citation: CAI Caihong, MEI Wenli, WANG Hui, DONG Wenhua, TAN Guanghong, DAI Haofu. Biological Activity of the Extracts from Ancistrocladus tectorius[J]. Journal of Tropical Biology, 2015, 6(2): 163-167. doi: 10.15886/j.cnki.rdswxb.2015.02.010
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