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Volume 8 Issue 2
Jun.  2017
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Article Navigation >  Journal of Tropical Biology  > 2017  >  8(2): 236-240

KONG Fandong, ZHOU Liman, MA Qingyun, HUANG Shengzhuo, ZHAO Youxing. Research Advances in the AIP-based Quorum Sensing Inhibitors of Gram-positive Bacteria[J]. Journal of Tropical Biology, 2017, 8(2): 236-240. doi: 10.15886/j.cnki.rdswxb.2017.02.019
Citation: KONG Fandong, ZHOU Liman, MA Qingyun, HUANG Shengzhuo, ZHAO Youxing. Research Advances in the AIP-based Quorum Sensing Inhibitors of Gram-positive Bacteria[J]. Journal of Tropical Biology, 2017, 8(2): 236-240. doi: 10.15886/j.cnki.rdswxb.2017.02.019
shu

Research Advances in the AIP-based Quorum Sensing Inhibitors of Gram-positive Bacteria

doi: 10.15886/j.cnki.rdswxb.2017.02.019

  • Institute of Tropical Bioscience and Biotechnology, Chinese Academy of Tropical Agricultural Sciences, Haikou, Hainan 571101, China

  • Received Date: 2016-10-25
  • Rev Recd Date: 2017-01-28
  • Quorum sensing（ QS） is a responding phenomenon of communication between bacteria,providing a new way to study treatment of bacterial infections. The QS system with autoinducter peptides（ AIPs） as signaling molecules exist in a variety of gram-positive bacteria,and is considered as an important breakthrough in development of new drugs against gram-positive bacteria,such as Staphylococcus aureus. The AIP-based quorum sensing inhibitors（ QSIs） discovered so far include two types of molecule,small and macro. The recent researches in these two types of molecule in AIP based QSIs were reviewed to provide a reference for developing of new antibacterial drugs.
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Research Advances in the AIP-based Quorum Sensing Inhibitors of Gram-positive Bacteria

doi: 10.15886/j.cnki.rdswxb.2017.02.019
  • Institute of Tropical Bioscience and Biotechnology, Chinese Academy of Tropical Agricultural Sciences, Haikou, Hainan 571101, China
  • Received Date: 2016-10-25
  • Rev Recd Date: 2017-01-28

Abstract: Quorum sensing（ QS） is a responding phenomenon of communication between bacteria,providing a new way to study treatment of bacterial infections. The QS system with autoinducter peptides（ AIPs） as signaling molecules exist in a variety of gram-positive bacteria,and is considered as an important breakthrough in development of new drugs against gram-positive bacteria,such as Staphylococcus aureus. The AIP-based quorum sensing inhibitors（ QSIs） discovered so far include two types of molecule,small and macro. The recent researches in these two types of molecule in AIP based QSIs were reviewed to provide a reference for developing of new antibacterial drugs.

KONG Fandong, ZHOU Liman, MA Qingyun, HUANG Shengzhuo, ZHAO Youxing. Research Advances in the AIP-based Quorum Sensing Inhibitors of Gram-positive Bacteria[J]. Journal of Tropical Biology, 2017, 8(2): 236-240. doi: 10.15886/j.cnki.rdswxb.2017.02.019
Citation: KONG Fandong, ZHOU Liman, MA Qingyun, HUANG Shengzhuo, ZHAO Youxing. Research Advances in the AIP-based Quorum Sensing Inhibitors of Gram-positive Bacteria[J]. Journal of Tropical Biology, 2017, 8(2): 236-240. doi: 10.15886/j.cnki.rdswxb.2017.02.019
shu

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