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Volume 7 Issue 1
Jan.  2016
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Article Navigation >  Journal of Tropical Biology  > 2016  >  7(1): 111-116

WANG Hongni, DONG Wenhua, MEI Wenli, LI Wei, GAI Cuijuan, DAI Haofu. Identification of Chemical Constituents of Agarwood of Aquilaria Crassna[J]. Journal of Tropical Biology, 2016, 7(1): 111-116. doi: 10.15886/j.cnki.rdswxb.2016.01.019
Citation: WANG Hongni, DONG Wenhua, MEI Wenli, LI Wei, GAI Cuijuan, DAI Haofu. Identification of Chemical Constituents of Agarwood of Aquilaria Crassna[J]. Journal of Tropical Biology, 2016, 7(1): 111-116. doi: 10.15886/j.cnki.rdswxb.2016.01.019
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Identification of Chemical Constituents of Agarwood of Aquilaria Crassna

doi: 10.15886/j.cnki.rdswxb.2016.01.019

  • 1. College of Horticulture and Landscape Architecture, Hainan University, Haikou, Hainan 570228;

  • 2. Ministry of Agriculture Key Laboratory of Biology and Genetic Resources of Tropical Crops/Institute of Tropical Bioscience and Biotechnology, Chinese Academy of Tropical Agricultural Sciences, Haikou, Hainan 571101;

  • 3. Hainan Engineering and Technology Research Center for Agarwood, Haikou, Hainan 571101, China

  • Received Date: 2015-11-27
  • Agarwood of Aquilaria crassna was extracted to analyze its chemical constituents,and 10 compounds were isolated from Et OAc fraction of the agarwood by column chromatography over silica gel,and Sephadex LH-20. Spectral analysis showed that the compounds were identified as 2-（2-phenylethyl） chromone（1）,6-methoxy-2-（2-phenylethyl） chromone（2）,2-[2-（4-methoxyphenyl） ethyl]chromone（3）,6-methoxy-2-[2-（4-methoxyphenyl） ethyl]chromone（4）,6,7-dimethoxy-2-（2-phenylethyl） chromone（5）,5-hydroxy-6-methoxy-2-[2-（4-methoxyphenyl） ethyl]chromone（6）,6-methoxy-2-[2-（3-methoxy-4-hydroxyphenyl） ethyl]chromone（7）,6-methoxy-2-[2-（3-hydroxy-4-methoxyphenyl） ethyl]chromone（8）,6-hydroxy-2-[2-（4-methoxyphenyl）ethyl] chromone（9）,and 6-hydroxy-2-[2-（3-hydroxy-4-methoxyphenyl） ethyl]chromone（10）. Compounds2-10 were isolated from the agarwood of Aquilaria crassna for the first time,and compounds 4,5,7 and 8showed inhibitory activity against acetylcholinesterase.
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Identification of Chemical Constituents of Agarwood of Aquilaria Crassna

doi: 10.15886/j.cnki.rdswxb.2016.01.019
  • 1. College of Horticulture and Landscape Architecture, Hainan University, Haikou, Hainan 570228;
  • 2. Ministry of Agriculture Key Laboratory of Biology and Genetic Resources of Tropical Crops/Institute of Tropical Bioscience and Biotechnology, Chinese Academy of Tropical Agricultural Sciences, Haikou, Hainan 571101;
  • 3. Hainan Engineering and Technology Research Center for Agarwood, Haikou, Hainan 571101, China
  • Received Date: 2015-11-27

Abstract: Agarwood of Aquilaria crassna was extracted to analyze its chemical constituents,and 10 compounds were isolated from Et OAc fraction of the agarwood by column chromatography over silica gel,and Sephadex LH-20. Spectral analysis showed that the compounds were identified as 2-（2-phenylethyl） chromone（1）,6-methoxy-2-（2-phenylethyl） chromone（2）,2-[2-（4-methoxyphenyl） ethyl]chromone（3）,6-methoxy-2-[2-（4-methoxyphenyl） ethyl]chromone（4）,6,7-dimethoxy-2-（2-phenylethyl） chromone（5）,5-hydroxy-6-methoxy-2-[2-（4-methoxyphenyl） ethyl]chromone（6）,6-methoxy-2-[2-（3-methoxy-4-hydroxyphenyl） ethyl]chromone（7）,6-methoxy-2-[2-（3-hydroxy-4-methoxyphenyl） ethyl]chromone（8）,6-hydroxy-2-[2-（4-methoxyphenyl）ethyl] chromone（9）,and 6-hydroxy-2-[2-（3-hydroxy-4-methoxyphenyl） ethyl]chromone（10）. Compounds2-10 were isolated from the agarwood of Aquilaria crassna for the first time,and compounds 4,5,7 and 8showed inhibitory activity against acetylcholinesterase.

WANG Hongni, DONG Wenhua, MEI Wenli, LI Wei, GAI Cuijuan, DAI Haofu. Identification of Chemical Constituents of Agarwood of Aquilaria Crassna[J]. Journal of Tropical Biology, 2016, 7(1): 111-116. doi: 10.15886/j.cnki.rdswxb.2016.01.019
Citation: WANG Hongni, DONG Wenhua, MEI Wenli, LI Wei, GAI Cuijuan, DAI Haofu. Identification of Chemical Constituents of Agarwood of Aquilaria Crassna[J]. Journal of Tropical Biology, 2016, 7(1): 111-116. doi: 10.15886/j.cnki.rdswxb.2016.01.019
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