[1] 李荣, 陈仪婷, 吕佳骏, 等. 上海市学龄儿童过敏性疾病流行现状及相关因素分析[J]. 中国学校卫生, 2021, 42(8): 1251−1256. https://doi.org/10.16835/j.cnki.1000-9817.2021.08.030 doi:  10.16835/j.cnki.1000-9817.2021.08.030
[2]

Li F, Zhou Y, Li S, et al. Prevalence and risk factors of childhood allergic diseases in eight metropolitan cities in China: a multicenter study [J]. BMC Public Health, 2011, 11(1): 437. https://doi.org/10.1186/1471-2458-11-437 doi:  10.1186/1471-2458-11-437
[3] 中华医学会变态反应分会呼吸过敏学组, 中华医学会呼吸病学分会哮喘学组. 中国过敏性哮喘诊治指南(第一版, 2019年)[J]. 中华内科杂志, 2019, 58(9): 636−655. https://doi.org/10.3760/cma.j.issn.0578-1426.2019.09.004 doi:  10.3760/cma.j.issn.0578-1426.2019.09.004
[4]

Gehring U, Heinrich J, Jacob B, et al. Respiratory symptoms in relation to indoor exposure to mite and cat allergens and endotoxins [J]. European Respiratory Journal, 2001, 18(3): 555−563. https://doi.org/10.1183/09031936.01.00096801 doi:  10.1183/09031936.01.00096801
[5]

Bousquet. Global Initiative for Asthma (GINA) and its objectives [J]. Clinical & Experimental Allergy, 2010, 30(S1): 2−5. https://doi.org/10.1046/j.1365-2222.2000.00088.x doi:  10.1046/j.1365-2222.2000.00088.x
[6]

Sharma S, Lackie P M, Holgate S T. Uneasy breather: the implications of dust mite allergens [J]. Clinical & Experimental Allergy, 2003, 33(2): 163−165. https://doi.org/10.1046/j.1365-2222.2003.01605.x doi:  10.1046/j.1365-2222.2003.01605.x
[7]

Liao E C, Hsieh C W, Chang C Y, et al. Enhanced allergic inflammation of Der p 2 affected by polymorphisms of MD-2 promoter [J]. Allergy, Asthma & Immunology Research, 2015, 7(5): 497−506. https://doi.org/10.4168/aair.2015.7.5.497 doi:  10.4168/aair.2015.7.5.497
[8]

Chua K Y, Stewart G A, Thomas W R, et al. Sequence analysis of cDNA coding for a major house dust mite allergen, Der p 1. Homology with cysteine proteases [J]. Journal of Experimental Medicine, 1988, 167(1): 175−182. https://doi.org/10.1084/jem.167.1.175 doi:  10.1084/jem.167.1.175
[9]

Waldron R, Mcgowan J, Gordon N, et al. Proteome and allergenome of the European house dust mite Dermatophagoides pteronyssinus [J]. PLoS One, 2019, 14(5): e0216171. https://doi.org/10.1371/journal.pone.0216171 doi:  10.1371/journal.pone.0216171
[10]

Thomas W R, Smith W A, Hales B J, et al. Characterization and immunobiology of house dust mite allergens [J]. International Archives of Allergy and Immunology, 2002, 129(1): 1−18. https://doi.org/10.1159/000065179 doi:  10.1159/000065179
[11]

Yi F C, Shek L P, Cheong N, et al. Molecular cloning of Blomia tropicalis allergens - a major source of dust mite allergens in the tropics and subtropics [J]. Inflammation & Allergy - Drug Targets, 2006, 5(4): 261−266. https://doi.org/10.2174/187152806779010954 doi:  10.2174/187152806779010954
[12]

Kuo I C, Cheong N, Trakultivakorn M, et al. An extensive study of human IgE cross-reactivity of Blo t 5 and Der p 5 [J]. Journal of Allergy and Clinical Immunology, 2003, 111(3): 603−609. https://doi.org/10.1067/mai.2003.167 doi:  10.1067/mai.2003.167
[13] 毕玉田, 吴奎, 王长征. 屋尘螨过敏原Der p1研究进展[J]. 重庆医学, 2007, 36(2): 171−173. https://doi.org/10.3969/j.issn.1671-8348.2007.02.040 doi:  10.3969/j.issn.1671-8348.2007.02.040
[14] 郑佩燕, 孙宝清. 屋尘螨致敏蛋白组分Derp1、Derp2和Derp10检测的临床意义[J]. 中华临床免疫和变态反应杂志, 2014, 8(2): 150−154. https://doi.org/10.3969/j.issn.1673-8705.2014.02.012 doi:  10.3969/j.issn.1673-8705.2014.02.012
[15]

Penagos M, Durham S R. Duration of allergen immunotherapy for inhalant allergy [J]. Current Opinion in Allergy and Clinical Immunology, 2019, 19(6): 594−605. https://doi.org/10.1097/ACI.0000000000000585 doi:  10.1097/ACI.0000000000000585
[16]

Passalacqua G, Durham S R. Allergic rhinitis and its impact on asthma update: allergen immunotherapy [J]. Rhinitis, Sinusitis, and Ocular Diseases, 2007, 119(4): 881−891. https://doi.org/10.1016/j.jaci.2007.01.045 doi:  10.1016/j.jaci.2007.01.045
[17]

Stewart-Tull D E S. Immunopotentiating conjugates [J]. Vaccine, 1985, 3(1): 40−44. https://doi.org/10.1016/0264-410X(85)90010-6 doi:  10.1016/0264-410X(85)90010-6
[18]

Alexander J, Fikes J, Hoffman S, et al. The optimization of helper T lymphocyte (HTL) function in vaccine development [J]. Immunologic Research, 1998, 18(2): 79−92. https://doi.org/10.1007/BF02788751 doi:  10.1007/BF02788751
[19]

Gurunathan S, Wu C Y, Freidag B L, et al. DNA vaccines: a key for inducing long-term cellular immunity [J]. Current Opinion in Immunology, 2000, 12(4): 442−447. https://doi.org/10.1016/S0952-7915(00)00118-7 doi:  10.1016/S0952-7915(00)00118-7
[20] 方芳. 重组MUC1-MBP融合蛋白疫苗抗肿瘤作用机制研究[D]. 长春: 吉林大学, 2010.
[21]

Jin H L, Xiao C, Geng S, et al. Protein/DNA vaccine-induced antigen-specific Treg confer protection against asthma [J]. European Journal of Immunology, 2008, 38(9): 2451−2463. https://doi.org/10.1002/eji.200737899 doi:  10.1002/eji.200737899
[22]

Casaro M, Souza V R, Oliveira F A, et al. OVA-induced allergic airway inflammation mouse model [J]. Methods in Molecular Biology, 2019, 1916: 297−301. https://doi.org/10.1007/978-1-4939-8994-2_28 doi:  10.1007/978-1-4939-8994-2_28
[23] 魏春洁, 徐琳皓, 高江瑞, 等. 猫、犬融合变应原Fel d 1-Can f 1过敏性哮喘小鼠模型的建立[J]. 热带生物学报, 2024, 15(5): 558−566. https://doi.org/10.15886/j.cnki.rdswxb.20240036 doi:  10.15886/j.cnki.rdswxb.20240036
[24] 肖正泮, 刘金莹, 韦双双, 等. 重组热带螨Blo t 21变应原诱导小鼠变态反应气道炎症模型的建立[J]. 热带生物学报, 2017, 8(3): 371−376. https://doi.org/10.15886/j.cnki.rdswxb.2017.03.020 doi:  10.15886/j.cnki.rdswxb.2017.03.020
[25]

Nair P, Hargreave F E. Measuring bronchitis in airway diseases: clinical implementation and application: airway hyperresponsiveness in asthma: its measurement and clinical significance [J]. Airway Hyperresponsiveness in Asthma: Its Measurement and Clinical Significance, 2010, 138(S2): 38S−43S. https://doi.org/10.1378/chest.10-0094 doi:  10.1378/chest.10-0094
[26]

Schoos A M M. Atopic diseases—Diagnostics, mechanisms, and exposures [J]. Pediatric Allergy and Immunology, 2024, 35(7): e14198. https://doi.org/10.1111/pai.14198 doi:  10.1111/pai.14198
[27]

Hamelmann E, Tadeda K, Oshiba A, et al. Role of IgE in the development of allergic airway inflammation and airway hyperresponsiveness–a murine model [J]. Allergy, 1999, 54(4): 297−305. https://doi.org/10.1034/j.1398-9995.1999.00085.x doi:  10.1034/j.1398-9995.1999.00085.x
[28]

Sawaguchi M, Tanaka S, Nakatani Y, et al. Role of mast cells and basophils in IgE responses and in allergic airway hyperresponsiveness [J]. The Journal of Immunology, 2012, 188(4): 1809−1818. https://doi.org/10.4049/jimmunol.1101746 doi:  10.4049/jimmunol.1101746
[29] 周书林, 常维佳, 姜玉新, 等. 重组粉尘螨Ⅱ类变应原致敏小鼠肺部变应性炎症模型的建立[J]. 中国媒介生物学及控制杂志, 2012, 23(3): 221−224.