[1] 中国科学院中国植物志编辑委员会. 中国植物志 第16卷 第2分册[M]. 北京: 科学出版社, 2016: 67-67.
[2] 国家药典委员会. 中华人民共和国药典[M]. 北京: 中国医药科技出版社: 2020: 303-304.
[3] 吴珊珊, 龚晓猛, 张美, 等. 缩泉丸中益智仁盐炙前后对肾阳虚大鼠肾脏功能的改善作用[J]. 中国实验方剂学杂志, 2016, 22(5), 1−4. https://doi.org/10.13422/j.cnki.syfjx.2016050001 doi:  10.13422/j.cnki.syfjx.2016050001
[4] 李海波, 周汨, 董洁, 等. 益智化学成分及药理作用研究进展[J]. 世界科学技术-中医药现代化, 2024, 26(7), 1870−1887. https://doi.org/10.11842/wst.20230519004 doi:  10.11842/wst.20230519004
[5]

BUSAYO F K, YANG J L, DING X P, et al. Identification of volatile compounds and their bioactivities from unpolar fraction of Alpinia oxyphylla Miq. and mining key genes of nootkatone biosynthesis [J]. Natural Product Research, 2024, 38 (10), 1793−1798. https://doi.org/10.1080/14786419.2023.2220063 doi:  10.1080/14786419.2023.2220063
[6]

DENG X M, YE Z L, DUAN J Y, et al. Complete pathway elucidation and heterologous reconstitution of (+)-nootkatone biosynthesis from Alpinia oxyphylla [J]. New Phytologist, 2024, 241 (2), 779−792. https://doi.org/10.1111/nph.19375 doi:  10.1111/nph.19375
[7] 罗京超, 冯毅凡, 吉星. 天然线性二苯基庚烷类化合物的研究进展[J]. 中草药, 2008, 39(12), 1912−1916. https://doi.org/10.3321/j.issn:0253-2670.2008.12.054 doi:  10.3321/j.issn:0253-2670.2008.12.054
[8]

MORITA H, WONG C P, ABE I. How structural subtleties lead to molecular diversity for the type III polyketide synthases [J]. Journal of Biological Chemistry, 2019, 294 (41), 15121−15136. https://doi.org/10.1074/jbc.REV119.006129 doi:  10.1074/jbc.REV119.006129
[9]

FERRER J L, JEZ J M, BOWMAN M E, et al. Structure of chalcone synthase and the molecular basis of plant polyketide biosynthesis [J]. Nature Structural Biology, 1999, 6 (8), 775−784. https://doi.org/10.1038/11553 doi:  10.1038/11553
[10]

KREUZALER F, HAHLBROCK K. Enzymatic synthesis of aromatic compounds in higher plants: formation of naringenin (5, 7, 4'-trihydroxyflavanone) from p-coumaroyl coenzyme A and malonyl coenzyme A [J]. Federation of European Biochemical Societies, 1972, 28 (1), 69−72. https://doi.org/10.1016/0014-5793(72)80679-3 doi:  10.1016/0014-5793(72)80679-3
[11]

KREUZALER F, RAGG H, FAUTZ E, et al. UV-induction of chalcone synthase mRNA in cell suspension cultures of Petroselinum hortense [J]. Proceedings of the National Academy of Sciences of the United States of America, 1983, 80 (9), 2591−2593. https://doi.org/10.1073/pnas.80.9.2591 doi:  10.1073/pnas.80.9.2591
[12]

KATSUYAMA Y, MIYAZONO K I, TANOKURA M, et al. Structural and biochemical elucidation of mechanism for decarboxylative condensation of β-keto acid by curcumin synthase [J]. Journal of Biological Chemistry, 2011, 286 (8), 6659−6668. https://doi.org/10.1074/jbc.M110.196279 doi:  10.1074/jbc.M110.196279
[13]

KATSUYAMA Y, KITA T, FUNA N, et al. Curcuminoid biosynthesis by two type III polyketide synthases in the herb Curcuma longa [J]. Journal of Biological Chemistry, 2009, 284 (17), 11160−11170. https://doi.org/10.1074/jbc.M900070200 doi:  10.1074/jbc.M900070200
[14]

WANG J, WANG X H, LIU X, et al. Synthesis of unnatural 2-substituted quinolones and 1, 3-diketones by a member of type III polyketide synthases from Huperzia serrata [J]. Organic Letters, 2016, 18 (15), 3550−3553. https://doi.org/10.1021/acs.orglett.6b01501 doi:  10.1021/acs.orglett.6b01501
[15]

SAKAMOTO S, MORITA Y, YUSAKUL G, et al. Molecular cloning and characterization of type III polyketide synthase from Plumbago zeylanica [J]. Journal of Asian Natural Products Research, 2021, 23 (5), 478−490. https://doi.org/10.1080/10286020.2020.1754399 doi:  10.1080/10286020.2020.1754399
[16]

CHOI G S, CHOO H J, KIM B G, et al. Synthesis of acridone derivatives via heterologous expression of a plant type III polyketide synthase in Escherichia coli [J]. Microbial Cell Factories, 2020, 19 (1), 73. https://doi.org/10.1186/s12934-020-01331-2 doi:  10.1186/s12934-020-01331-2
[17]

ZHOU S G, ZHONG K, YAN F X, et al. Biological characteristics of a novel bibenzyl synthase (DoBS1) gene from Dendrobium officinale catalyzing dihydroresveratrol synthesis [J]. Molecules, 2024, 29 (22), 5320. https://doi.org/10.3390/molecules29225320 doi:  10.3390/molecules29225320
[18]

CHEN Y, WANG Y, LIANG C J, et al. Characterization of the key bibenzyl synthase in Dendrobium sinense [J]. International Journal of Molecular Sciences, 2022, 23 (12), 6780. https://doi.org/10.3390/ijms23126780 doi:  10.3390/ijms23126780
[19]

WANG X H, GAO B W, NAKASHIMA Y, et al. Identification of a diarylpentanoid-producing polyketide synthase revealing an unusual biosynthetic pathway of 2-(2-phenylethyl)chromones in agarwood [J]. Nature Communications, 2022, 13 (1), 348. https://doi.org/10.1038/s41467-022-27971-z doi:  10.1038/s41467-022-27971-z
[20]

MANOILENKO S, DIPPE M, FUCHS T, et al. Enzymatic one-step synthesis of natural 2-pyrones and new-to-nature derivatives from coenzyme A esters [J]. Journal of Biotechnology, 2024, 388, 72−82. https://doi.org/10.1016/j.jbiotec.2024.04.006 doi:  10.1016/j.jbiotec.2024.04.006
[21]

TAKEMOTO K, MIKOTA Y, MORIUCHI R, et al. Cloning of three Alnus sieboldiana type III polyketide synthases and formation of polyketides in recombinant Escherichia coli using cinnamic acid analogs as substrates [J]. Heliyon, 2024, 10 (6), e27698. https://doi.org/10.1016/j.heliyon.2024.e27698 doi:  10.1016/j.heliyon.2024.e27698
[22]

PAN K, DAI S P, TIAN J P, et al. Chromosome-level genome and multi-omics analyses provide insights into the geo-herbalism properties of Alpinia oxyphylla [J]. Frontiers in Plant Science, 2023, 14, 1161257. https://doi.org/10.3389/fpls.2023.1161257 doi:  10.3389/fpls.2023.1161257
[23] 李成磊, 张晓伟, 吴琦, 等. 甜荞查尔酮合酶基因Chs的克隆及序列分析[J]. 广西植物, 2011, 31(3), 383−387. https://doi.org/10.3969/j.issn.1000-3142.2011.05.019 doi:  10.3969/j.issn.1000-3142.2011.05.019
[24]

ABE I, MORITA H. Structure and function of the chalcone synthase superfamily of plant type III polyketide synthases [J]. Natural Product Reports, 2010, 27 (6), 809−838. https://doi.org/10.1039/b909988n doi:  10.1039/b909988n
[25]

GOYAL M, CHAUDHURI T K. GroEL-GroES assisted folding of multiple recombinant proteins simultaneously over-expressed in Escherichia coli [J]. The International Journal of Biochemistry & Cell Biology, 2015, 64, 277−286. https://doi.org/10.1016/j.biocel.2015.04.018 doi:  10.1016/j.biocel.2015.04.018
[26]

STEWART C, Jr, WOODS K, MACIAS G, et al. Molecular architectures of benzoic acid-specific type III polyketide synthases[J]. Acta Crystallographica Section D: Structural Biology, 2017, 73(Pt 12): 1007-1019. https://doi.org/10.1107/S2059798317016618 doi:  10.1107/S2059798317016618