[1] WANG J H, LU J, ZHANG Y X, et al. Metagenomic analysis of antibiotic resistance genes in coastal industrial mariculture systems [J]. Bioresour Technol, 2018, 189(12): 235 − 43.
[2] YANG CHANGWON, SONG GWONHWA, LIM WHASUN. A review of the toxicity in fish exposed to antibiotics [J]. Comp Biochem Physiol C Toxicol Pharmacol, 2020, 237: 108840. doi:  10.1016/j.cbpc.2020.108840
[3] FAO/WHO. Health and nutritional properties of probiotics in food including powder milk with live lactic acid bacteria[R]. Córdoba, Argentina. 2001.
[4] SOKOL H, LAY C, SEKSIK P, et al. Analysis of bacterial bowel communities of IBD patients: What has it revealed? [J]. Inflammatory Bowel Diseases, 2008, 14: 858 − 867. doi:  10.1002/ibd.20392
[5] FUESS L, DEN HAAN S, LING F, et al. Immune gene expression covaries with gut microbiome composition in stickleback [J]. mBio, 2021, 12(3): e00145 − 21.
[6] 张美玲, 单承杰, 杜震宇. 益生菌与鱼类肠道健康研究进展[J]. 水产学报, 2021(1): 11.
[7] 廖庆钊, 陈福艳, 覃雅, 等. 投喂乙醇假丝酵母对罗非鱼生长、免疫和肠道菌群的影响[J]. 南方水产科学, 2021, 17(5): 10 − 17. doi:  10.12131/20200258
[8] LI H, ZHOU Y, LING H, et al. The effect of dietary supplementation with Clostridium butyricum on the growth performance, immunity, intestinal microbiota and disease resistance of tilapia (Oreochromis niloticus) [J]. PLoS One, 2019, 14(12): e0223428. doi:  10.1371/journal.pone.0223428
[9] GONCALVES A T, GALLARDO-ESCÁRATE C. Microbiome dynamic modulation through functional diets based on pre- and probiotics (mannan-oligosaccharides and Saccharomyces cerevisiae) in juvenile rainbow trout (Oncorhynchus mykiss) [J]. J Appl Microbiol, 2017, 122: 1333 − 1347. doi:  10.1111/jam.13437
[10] MIYAMOTO-SHINOHARA Y, SUKENOBE J, IMAIZUMI T, et al. Survival of freeze-dried bacteria [J]. Journal of General & Applied Microbiology, 2008, 54(1): 9 − 24.
[11] CONRAD P B, MILLER D P, CIELENSKI P R, et al. Stabilization and preservation of Lactobacillus acidophilus in saccharide matrices [J]. Cryobiology, 2000, 41(1): 17 − 24. doi:  10.1006/cryo.2000.2260
[12] HUBáLEK Z. Protectants used in the cryopreservation of microorganisms [J]. Cryobiology, 2003, 46(3): 205 − 229. doi:  10.1016/S0011-2240(03)00046-4
[13] ZAYED G, ROOS Y H. Influence of trehalose and moisture content on survival of Lactobacillus salivarius subjected to freeze-drying and storage [J]. Process Biochemistry, 2004, 39(9): 1081 − 1086. doi:  10.1016/S0032-9592(03)00222-X
[14] CELIK O F, O'SULLIVAN D J. Factors influencing the stability of freeze-dried stress-resilient and stress-sensitive strains of bifidobacteria [J]. J Dairy Sci, 2013, 96: 3506 − 16. doi:  10.3168/jds.2012-6327
[15] MACKENZIE A P. Comparative studies on the freeze-drying survival of various bacteria: gram type, suspending medium, and freezing rate [J]. Developments in Biological Standardization, 1976, 36: 263 − 77.
[16] BRENNAN M, WANISMAIL B, JOHNSON M C, et al. Cellular damage in dried Lactobacillus acidophilus [J]. Journal of Food Protection, 1986, 49(1): 47 − 53. doi:  10.4315/0362-028X-49.1.47
[17] LEE J. ATCC preservation methods: freezing and freeze-drying [J]. Journal of Eukaryotic Microbiology, 1992, 39(5): 651 − 651.
[18] BRAVO-FERRADA B M, BRIZUELA N, GERBINO E, et al. Effect of protective agents and previous acclimation on ethanol resistance of frozen and freeze-dried Lactobacillus plantarum strains [J]. Cryobiology, 2015, 71(3): 522 − 528. doi:  10.1016/j.cryobiol.2015.10.154
[19] LESLIE S B, ISRAELI E, LIGHTHART B, et al. Trehalose and sucrose protect both membranes and proteins in intact bacteria during drying [J]. Applied & Environmental Microbiology, 1995, 61(10): 78 − 88.
[20] CARVALHO ANA S, SILVA JOANA, HO PETER, et al. Effects of various sugars added to growth and drying media upon thermotolerance and survival throughout storage of freeze-dried Lactobacillus delbrueckii ssp. bulgaricus [J]. Biotechnol Prog, 2010, 20(1): 248 − 254.
[21] OKOLIEGBE I L, SOLOMON L, DICK A. Exploiting microbial communities associated with marine fish: an indispensable approach to sustainable aquaculture [J]. Nature and Science, 2017, 15(4): 84 − 91.
[22] TAN H Y, CHEN S W, HU S Y. Improvements in the growth performance, immunity, disease resistance, and gut microbiota by the probiotic Rummeliibacillus stabekisii in Nile tilapia (Oreochromis niloticus) [J]. Fish & Shellfish Immunology, 2019, 92: 265 − 275.
[23] XIA Y, LU M, CHEN G, et al. Effects of dietary Lactobacillus rhamnosus JCM1136 and Lactococcus lactis subsp. lactis JCM5805 on the growth, intestinal microbiota, morphology, immune response and disease resistance of juvenile Nile tilapia, Oreochromis niloticus [J]. Fish & shellfish immunology, 2018, 76: 368 − 379.
[24] FINEGOLD S M, VAISANEN M L, MOLITORIS D R, et al. Cetobacterium somerae sp. nov. from human feces and emended description of the genus cetobacterium [J]. Systematic and Applied Microbiology, 2003, 26(2): 177 − 181. doi:  10.1078/072320203322346010
[25] NGUYEN D T, LOPEZ-PORRAS A, MARANCIK D, et al. Genetic characterization of heterologous Edwardsiella piscicida isolates from diverse fish hosts and virulence assessment in a Chinook salmon Oncorhynchus tshawytscha model [J]. J Fish Dis, 2021, 44(12): 1959 − 1970. doi:  10.1111/jfd.13509
[26] ZHANG H, CHEN M, XU Y, et al. An effective live attenuated vaccine against Aeromonas veronii infection in the loach (Misgurnus anguillicaudatus) [J]. Fish & shellfish immunology, 2020, 104: 269 − 278.
[27] TOOBA L, SHAHZAD A, ZAHID M, et al. Molecular characterization of Aeromonas hydrophila isolates from diseased fishes in district Kasur, Punjab, Pakistan [J]. Brazilian journal of biology Revista brasleira de biologia, 2022, 84: e254816.